I've tried all three and learned something from each. The .308 is my reliable choice and good for my usual hunting distances. The .300 Win Mag gave me extra range but the recoil was noticeable...the 7mm Rem Mag was a surprise, it shot flatter than the .308 and kicked a bit less than the .300 in my rifles. I'm still figuring out my favorite for general use, if you've used these calibers a lot, which one suits you best?